As healthcare organizations move beyond pilot programs, the priority shifts to building a resilient, long-term infrastructure for the secondary use of medical data. This keynote introduces Patient Journey Intelligence as the industry’s first agentic operating system designed to transform raw, multimodal clinical records into high-fidelity, OMOP-standardized longitudinal datasets. Central to this mission is a framework of FDA-aligned governance, providing auditable transparency across privacy, data provenance, and AI ethics – ensuring that autonomous workflows remain safe, compliant, and reproducible.

The session features a live demonstration of the platform’s Agentic AI capabilities, moving from static data retrieval to active clinical reasoning. We will show how researchers can use no-code agentic environments like Claude Code, Codex, and Cursor to automate complex end-to-end workflows directly on top of an OMOP data foundation. From:

• Matching patients to clinical trials
• Identifying care gaps against clinical guidelines
• Automating patient registries

We illustrate how a governed agentic approach can slash discovery timelines while maintaining the highest regulatory standards for real-world evidence.